MeansTests One group t Paired t Student’s t-test (equal variances) Sattherthwaite’s t-test (unequal variances) Two group t-test for fold change assuming log-normal distribution Two group t-test of equal fold change with fold change threshold Crossover (2x2) One way analysis of variance Two way analysis of variance Repeated measures ANOVA (one and two group) Contrasts Confidence Intervals One group Paired design Two group Contrasts For normal limits One sided and TOST Equivalence Tests Paired design Two group (difference in means) Two group (ratio of means) Crossover (difference in means) Crossover (ratio of means) Agreement One Group Tests and Confidence Intervals Kappa Correlation coefficient Lin’s concordance coefficient Intra-class correlation Regression
Tests and Confidence Intervals Logistic regression (one or multiple covariates) Linear regression Multiple regression Multiple regression (with partialling) Tests and confidence intervals for regression slopes in one and two sample designs Plots
Multiple plot options allowing user specification of x and y axes (power vs n, interval width vs n, and power or n versus effect size)
Create Randomization Lists Create randomization lists for simple or complex studies with centers, strata, unequal treatment assignments Select block sizes and use ID numbering options | | ProportionsTests One group binomial (exact) Paired (McNemar’s and exact tests) Two group Chi-square Continuity corrected Chi-square Fisher’s Exact Test Gx2 table Chi-square Logistic model for Gx2 table Cochran / Mantel - Haenszel Goodness of fit, C categories Two - group, C categories G - group, C categories Confidence Intervals One group binomial One group binomial (rare event) Paired design (odds ratio) Two group (difference/odds ratio) Two group (relative risk) One sided and TOST Equivalence Tests For paired proportions For two independent proportions Nonparametric
Tests Wilcoxon/Mann-Whitney rank-sum test (continuous outcome or ordered scale) Survival
Two group Tests Test of exponential survival (accrual/dropouts) Log-rank test (simulation) for user-specified accrual, hazard rates, dropout rates (equal and unequal n’s) Non-inferiority test Features
Equal or unequal n’s Finite population corrections Cluster sample corrections Kupper-Hafner CI modification Plots Statements Effect size assistance References Standard deviation calculator Column names Tables, statements, guides in RTF format Decimal display controls Create randomization list |